How does stem cell therapy help ALS?

MSCs provide neuroprotective support for motor neurons, reduce neuroinflammation, release neurotrophic factors that slow motor neuron degeneration, and may promote formation of new neural connections. The goal is to slow disease progression and preserve existing function.

Can stem cell therapy slow ALS progression?

Clinical studies show MSC therapy can slow the rate of decline on the ALSFRS-R scale in ALS patients. While not a cure, many patients experience stabilization of symptoms and preserved function longer than expected with standard care alone.

When should ALS patients consider stem cell therapy?

Earlier intervention generally yields better results, as there are more motor neurons to protect. However, patients at all stages can benefit from the neuroprotective and anti-inflammatory effects. We evaluate each case individually.

What delivery method is used for ALS stem cell therapy?

Our ALS protocol uses combined IV infusion and intrathecal injection to maximize both systemic immune modulation and direct delivery of MSCs to the central nervous system, providing the best chance of reaching affected motor neurons.

ALS (Motor Neuron Disease) Stem Cell Therapy in Istanbul, Turkey

Stem cell therapy for ALS (amyotrophic lateral sclerosis). MSC treatments provide neuroprotection for motor neurons, reduce neuroinflammation, and release neurotrophic factors to slow disease progression.

About Als Stem Cell Therapy in Istanbul

Stem cell therapy for ALS (amyotrophic lateral sclerosis / motor neuron disease) at StemCell Longevita in Istanbul provides neuroprotective support for motor neurons, reduces neuroinflammation, and aims to slow disease progression. While not a cure, our MSC treatments help patients preserve function and maintain quality of life longer than standard care alone.

How Stem Cell Therapy Works for This Condition

ALS involves progressive degeneration of motor neurons in the brain and spinal cord. MSCs provide neuroprotection through multiple mechanisms: releasing neurotrophic factors (GDNF, BDNF, VEGF, IGF-1) that support motor neuron survival, suppressing microglial activation and neuroinflammation that accelerate motor neuron death, promoting neural repair pathways, and improving spinal cord blood flow. The goal is to slow the rate of motor neuron loss and preserve existing function.

Who Is a Candidate?

Patients with diagnosed ALS at any stage, though earlier intervention yields better results as more motor neurons remain to protect. Patients with progressive muscular atrophy, primary lateral sclerosis, and progressive bulbar palsy may also benefit. Our neurological team evaluates ALSFRS-R scores and rate of decline to guide treatment decisions.

Treatment Process at StemCell Longevita

After neurological evaluation including ALSFRS-R scoring and electrophysiological studies, treatment involves combined IV and intrathecal MSC delivery. The intrathecal route is critical for ALS to deliver cells directly to the spinal fluid bathing the affected motor neurons. Multiple treatment sessions at 3-6 month intervals are typically recommended.

Expected Results & Recovery

Potential stabilization or slowed decline on ALSFRS-R scores, preserved respiratory function longer, maintained motor function in affected limbs, reduced fasciculations, and improved quality of life. Results are most meaningful when treatment begins early and is repeated regularly.

Why Choose Turkey for Treatment?

Istanbul's neurological team has specific expertise in motor neuron disease. Combined IV + intrathecal MSC delivery protocol at costs 60-80% lower than Western ALS clinical programs.

Cost of Treatment

ALS stem cell therapy from €8,500, including neurological assessment, combined IV + intrathecal MSC protocol, hotel, transfers, and ongoing follow-up.

Part of Our Neurological Conditions Treatment Cluster

Neurological Conditions — Treatment Cluster

Pillar: stem cell therapy for neurological conditions in Istanbul

Research & guides: stem cell therapy for cerebral palsy research | MSC treatment for autism spectrum disorder | stem cell therapy for stroke recovery in Turkey | MSC treatment for spinal cord injury rehabilitation

Frequently Asked Questions About ALS (Motor Neuron Disease) Stem Cell Therapy

How does stem cell therapy help ALS?: MSCs provide neuroprotective support for motor neurons, reduce neuroinflammation, release neurotrophic factors that slow motor neuron degeneration, and may promote formation of new neural connections. The goal is to slow disease progression and preserve existing function.
Can stem cell therapy slow ALS progression?: Clinical studies show MSC therapy can slow the rate of decline on the ALSFRS-R scale in ALS patients. While not a cure, many patients experience stabilization of symptoms and preserved function longer than expected with standard care alone.
When should ALS patients consider stem cell therapy?: Earlier intervention generally yields better results, as there are more motor neurons to protect. However, patients at all stages can benefit from the neuroprotective and anti-inflammatory effects. We evaluate each case individually.
What delivery method is used for ALS stem cell therapy?: Our ALS protocol uses combined IV infusion and intrathecal injection to maximize both systemic immune modulation and direct delivery of MSCs to the central nervous system, providing the best chance of reaching affected motor neurons.