How does stem cell therapy treat lupus?

MSCs reset the dysregulated immune system in lupus by suppressing autoreactive T and B cells, reducing inflammatory cytokine production, and promoting regulatory T cell generation. This helps control disease activity and reduce organ damage.

Can stem cell therapy reduce lupus flares?

Many lupus patients experience significant reduction in flare frequency and severity after MSC therapy. Studies show improvements in SLEDAI scores, reduced anti-dsDNA antibodies, and improved complement levels lasting 12+ months.

What lupus symptoms improve with stem cell therapy?

Patients report improvements in joint pain, fatigue, skin rashes, kidney function (in lupus nephritis), and overall energy levels. Many are able to reduce immunosuppressive medication doses under medical supervision.

How many stem cell treatments are needed for lupus?

Most lupus patients receive 1-2 initial treatment sessions with 50-100 million MSCs. Response is typically observed within 1-3 months. Follow-up treatments at 6-12 month intervals help maintain remission.

Lupus (SLE) Stem Cell Therapy in Istanbul, Turkey

Stem cell therapy for lupus (SLE). MSC treatments reset the dysregulated immune system, suppress autoreactive immune cells, reduce inflammatory cytokines, and protect organs from autoimmune damage.

About Lupus Stem Cell Therapy in Istanbul

Stem cell therapy for lupus (systemic lupus erythematosus / SLE) at StemCell Longevita in Istanbul resets the dysregulated immune system, reduces autoantibody production, and protects organs from autoimmune damage. Our MSC treatments help patients achieve disease control with reduced medication dependence.

How Stem Cell Therapy Works for This Condition

SLE involves loss of immune tolerance with autoreactive B-cells producing antibodies against the body's own DNA and tissues. MSCs suppress autoreactive T and B cells, reduce anti-dsDNA antibody levels, promote regulatory T-cell generation to restore immune tolerance, suppress inflammatory cytokine production, and protect kidneys, skin, joints, and other organs from ongoing autoimmune damage. Studies show improvements in SLEDAI scores and complement levels lasting 12+ months.

Who Is a Candidate?

Patients with moderate-to-severe SLE, lupus nephritis, cutaneous lupus, and those with active disease despite standard immunosuppressive therapy. Also beneficial for patients experiencing medication side effects or seeking to reduce steroid dependence.

Treatment Process at StemCell Longevita

After comprehensive immunological workup (ANA, anti-dsDNA, complement levels, CBC, renal function), treatment involves systemic IV MSC infusion with 50-100 million cells. Most patients receive 1-2 initial sessions.

Expected Results & Recovery

Improved SLEDAI scores, reduced anti-dsDNA antibodies, improved complement levels (C3, C4), decreased proteinuria in lupus nephritis, reduced joint pain, improved skin lesions, and enhanced energy levels within 1-3 months. Many patients reduce steroid and immunosuppressive doses under medical supervision.

Why Choose Turkey for Treatment?

Our immunology team has treated numerous lupus patients from across the globe. Istanbul provides comprehensive autoimmune evaluation and treatment at costs 60-80% lower than US or European rheumatology centers.

Cost of Treatment

Lupus stem cell therapy from €7,000, including immunological assessment, MSC infusion, hotel, transfers, and 12-month follow-up.

Part of Our Autoimmune Diseases Treatment Cluster

Autoimmune Diseases — Treatment Cluster

Pillar: MSC treatment for autoimmune diseases in Turkey

Research & guides: how MSC therapy modulates the immune system | stem cell therapy for autoimmune diseases in Istanbul

Frequently Asked Questions About Lupus (SLE) Stem Cell Therapy

How does stem cell therapy treat lupus?: MSCs reset the dysregulated immune system in lupus by suppressing autoreactive T and B cells, reducing inflammatory cytokine production, and promoting regulatory T cell generation. This helps control disease activity and reduce organ damage.
Can stem cell therapy reduce lupus flares?: Many lupus patients experience significant reduction in flare frequency and severity after MSC therapy. Studies show improvements in SLEDAI scores, reduced anti-dsDNA antibodies, and improved complement levels lasting 12+ months.
What lupus symptoms improve with stem cell therapy?: Patients report improvements in joint pain, fatigue, skin rashes, kidney function (in lupus nephritis), and overall energy levels. Many are able to reduce immunosuppressive medication doses under medical supervision.
How many stem cell treatments are needed for lupus?: Most lupus patients receive 1-2 initial treatment sessions with 50-100 million MSCs. Response is typically observed within 1-3 months. Follow-up treatments at 6-12 month intervals help maintain remission.