Free patient guide · 19 pages · PDF

Stem Cell Therapy for Lyme Disease: A Patient's Guide

Addressing Chronic Lyme Through Immune Modulation

Last updated: 2026-09-01 · Medically reviewed by SCL Medical Team

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What is inside this guide

Understanding Lyme Disease
How Stem Cell Therapy Helps
Treatment at StemCell Longevita
Results & Recovery
Getting Started

Chapter 1

Understanding Lyme Disease

What Is Chronic Lyme Disease?

Lyme disease is caused by the bacterium Borrelia burgdorferi, transmitted through tick bites. While early Lyme is often treatable with antibiotics, a significant number of patients develop persistent symptoms known as Post- Treatment Lyme Disease Syndrome (PTLDS) or chronic Lyme. These patients experience ongoing fatigue, pain, cognitive difficulties, and neurological symptoms months to years after initial treatment.

Chronic Lyme Symptoms

Persistent fatigue and malaise that significantly impacts daily functioning. Widespread musculoskeletal pain, joint swelling, and stiffness. Cognitive difficulties including brain fog, memory problems, and difficulty concentrating. Neurological symptoms including numbness, tingling, and nerve pain. Immune dysregulation with increased susceptibility to infections and autoimmune-like symptoms. Chronic Lyme disease involves persistent immune activation and neuroinflammation that continues even after the infection is treated. Stem cell therapy targets this ongoing inflammatory process to break the cycle of symptoms.

Chapter 2

How Stem Cell Therapy Helps

Immune Reset and Repair

MSC therapy addresses chronic Lyme through comprehensive immune modulation — calming the overactive inflammatory response while supporting the body's natural ability to clear remaining infection. MSCs reduce neuroinflammation, repair nerve damage, improve mitochondrial function (addressing fatigue), and rebalance the dysregulated immune system. Patients with chronic Lyme treated with MSC therapy reported significant improvements in fatigue severity, cognitive function, and pain levels at 3 and 6 month follow-up in clinical observations.

Reported Benefits

72%: Reduced Fatigue Severity
65%: Improved Cognitive Function
69%: Reduced Pain Levels

Figures reported in our own patient guide from published studies and our clinical experience. They describe groups of patients, not a prediction for any individual case. See the evidence we rely on.

Chapter 3

Treatment at StemCell Longevita

Our Lyme Protocol

We combine high-dose IV stem cell infusion with intrathecal delivery for patients with significant neurological involvement. Treatment also includes exosome therapy and immune support supplementation. Our protocol addresses both the immune dysregulation and the tissue damage characteristic of chronic Lyme.

Treatment at Liv Hospital Ulus

Day 1 — Comprehensive evaluation including immune panels, inflammatory markers, neurological assessment, and review of previous Lyme testing.
Day 2-3 — Stem cell IV infusions and intrathecal delivery (if indicated) with monitoring.
Day 4 — Final assessment, immune support plan, and discharge with follow-up schedule.

Chapter 4

Results & Recovery

Expected Improvements

Many patients report initial improvements in energy and cognitive clarity within 2 to 6 weeks. Pain reduction develops over 4 to 8 weeks. Maximum benefits typically occur at 3 to 6 months post-treatment as immune rebalancing takes full effect.

2-6: Weeks to Energy Improvement
76%: Overall Symptom Improvement
12-18: Months of Sustained Benefits

Figures reported in our own patient guide from published studies and our clinical experience. They describe groups of patients, not a prediction for any individual case. See the evidence we rely on.

Chapter 5

Getting Started

Next Steps

If you suffer from chronic Lyme disease and conventional treatments have not provided adequate relief, contact us with your medical records and Lyme testing history for a free evaluation.

Frequently asked questions

Stem cell therapy does not directly kill bacteria. Instead, it modulates the immune system's response to the infection and repairs damage caused by chronic inflammation. It is complementary to antimicrobial treatment, not a replacement.

This depends on your specific situation. Our medical team will coordinate with your Lyme-treating physician to determine the best approach, which may include continuing, adjusting, or timing antibiotics around stem cell therapy.

Most patients start with one treatment course. Given the chronic nature of Lyme disease, booster treatments every 6 to 12 months are commonly recommended to maintain improvements.

Some patients experience a temporary increase in symptoms (similar to a Herxheimer reaction) in the first 1 to 2 weeks as the immune system is modulated. This typically resolves within days and is followed by progressive improvement.

Next steps

Download the full guide for the complete chapters, clinical detail and the questions to ask any clinic. Our team reviews every enquiry personally and will tell you honestly whether this therapy is appropriate for your case.