Which neurological conditions does this program treat?

Our program addresses autism spectrum disorder, cerebral palsy, multiple sclerosis, Parkinson's disease, stroke recovery, dementia, and traumatic brain injury. Each condition requires a tailored protocol — for example, intrathecal delivery for MS and cerebral palsy, versus primarily IV for Parkinson's.

How many treatment sessions are needed?

Most patients receive 2–3 MSC infusion sessions during a 5–7 day stay. Some conditions benefit from a second treatment cycle 6–12 months later, which is assessed during follow-up consultations.

What improvements can we expect for a child with cerebral palsy?

Clinical studies show improvements in motor function (GMFM scores), muscle tone reduction, and cognitive gains. Many families report better mobility, speech development, and daily living independence within 3–6 months. Individual results vary and are discussed during the initial assessment.

Is the intrathecal procedure painful or risky?

Intrathecal administration is performed under local anaesthesia and is similar to a lumbar puncture. It is well-tolerated by most patients, including children. Mild headache may occur for 24–48 hours post-procedure. The procedure is performed by experienced clinicians in a hospital setting.

Neuro-Rehabilitation & Developmental Program — Stem Cell Therapy Istanbul

Comprehensive neuro-rehabilitation program at StemCell Longevita Istanbul combining mesenchymal stem cell therapy with intensive rehabilitation protocols. Designed for neurological conditions including autism, cerebral palsy, stroke recovery, multiple sclerosis, Parkinson's disease, ALS, spinal cord injury, and dementia.

Program Overview

Our Neuro-Rehabilitation & Developmental Program is designed for patients with neurological conditions ranging from childhood developmental disorders to adult neurodegenerative diseases. Under the direction of Prof. Dr. Erdal Karaöz — with over 190 peer-reviewed publications and 4,961 citations — we combine Wharton's jelly-derived MSC therapy with a structured rehabilitation framework.

Unlike isolated treatments, this program takes a holistic approach: pre-treatment neurological assessment, targeted cell therapy, integrated physiotherapy and occupational therapy, and a 12-month remote monitoring program. Our GMP-certified laboratory ensures every cell preparation meets pharmaceutical-grade quality standards.

Program at a Glance

Expected Stay: 5–7 days in Istanbul
Treatment Sessions: 2–3 MSC infusion sessions
Follow-Up Program: Video consultations at 1, 3, 6, and 12 months
Protocol: Wharton's jelly MSCs via IV + intrathecal (200–300 million cells)
Starting From: €8,950 all-inclusive

Your Treatment Journey

Pre-Arrival Assessment: Full medical records review, MRI and neuroimaging analysis, functional assessment scales (GMFM, EDSS, UPDRS), blood work panel, and personalised care plan development.
On-Site Clinical Assessment: Physical and neurological examination at Liv Hospital Ulus, baseline functional measurements, treatment protocol confirmation, and meeting your dedicated medical team.
Treatment Phase: Wharton's jelly MSC preparation in GMP clean-room lab, IV infusion plus intrathecal administration (for CNS conditions), real-time vital sign monitoring, and post-infusion observation.
Recovery & Integration: Physiotherapy, occupational therapy, speech therapy sessions, nutritional guidance, and discharge planning with detailed medical report.
Long-Term Follow-Up: Video consultations at 1, 3, 6, and 12 months, functional outcome tracking, optional second treatment cycle planning, and 24/7 medical support line access.

Treatment Protocols

Wharton's Jelly MSC Infusion: 200–300 million GMP-certified mesenchymal stem cells administered intravenously across 2–3 sessions. These cells home to sites of neurological damage, reducing inflammation and promoting neuroregeneration.
Intrathecal Administration: For central nervous system conditions (MS, cerebral palsy, spinal cord involvement), MSCs are delivered directly into the cerebrospinal fluid via lumbar puncture for direct brain and spinal cord access.
Exosome Therapy (Adjunctive): MSC-derived exosomes may be used as a complementary therapy, providing cell-free regenerative signalling molecules that cross the blood-brain barrier.
Rehabilitation Integration: Intensive physiotherapy, occupational therapy, and speech therapy sessions are integrated around treatment days to maximise functional gains.

Integrated Supportive Care

Neurological physiotherapy with certified specialists
Occupational therapy for daily living skills improvement
Speech and language therapy (for applicable conditions)
Anti-inflammatory and neuroprotective nutrition plan
Hyperbaric oxygen therapy (HBOT) when indicated
Cognitive rehabilitation exercises
Family education and home care training

Conditions Treated

Frequently Asked Questions

Which neurological conditions does this program treat?: Our program addresses autism spectrum disorder, cerebral palsy, multiple sclerosis, Parkinson's disease, stroke recovery, dementia, and traumatic brain injury. Each condition requires a tailored protocol — for example, intrathecal delivery for MS and cerebral palsy, versus primarily IV for Parkinson's.
How many treatment sessions are needed?: Most patients receive 2–3 MSC infusion sessions during a 5–7 day stay. Some conditions benefit from a second treatment cycle 6–12 months later, which is assessed during follow-up consultations.
What improvements can we expect for a child with cerebral palsy?: Clinical studies show improvements in motor function (GMFM scores), muscle tone reduction, and cognitive gains. Many families report better mobility, speech development, and daily living independence within 3–6 months. Individual results vary and are discussed during the initial assessment.
Is the intrathecal procedure painful or risky?: Intrathecal administration is performed under local anaesthesia and is similar to a lumbar puncture. It is well-tolerated by most patients, including children. Mild headache may occur for 24–48 hours post-procedure. The procedure is performed by experienced clinicians in a hospital setting.