Free patient guide · 19 pages · PDF

Stem Cell Therapy for Multiple Sclerosis: A Patient's Guide

Modulating Immunity and Supporting Myelin Repair

Last updated: 2026-09-01 · Medically reviewed by SCL Medical Team

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What is inside this guide

Understanding Multiple Sclerosis
How Stem Cell Therapy Helps
Treatment at StemCell Longevita
Results & Recovery
Getting Started

Chapter 1

Understanding Multiple Sclerosis

What Is Multiple Sclerosis?

Multiple Sclerosis (MS) is a chronic autoimmune disease in which the immune system attacks the myelin signal transmission, causing a wide range of neurological symptoms. MS affects approximately 2.8 million people worldwide, with onset typically between ages 20 and 40.

sheath — the protective covering of nerve fibers in the brain and spinal cord. This demyelination disrupts nerve

Types and Symptoms

Common symptoms include fatigue, walking difficulties, numbness, vision problems, spasticity, and cognitive changes. MS involves both inflammatory attacks on myelin and progressive neurodegeneration. Stem cell therapy addresses both aspects by modulating the autoimmune response and supporting neural repair.

Relapsing-Remitting MS (RRMS) — The most common form, characterized by periods of new or worsening symptoms (relapses) followed by partial or complete recovery (remissions).
Secondary Progressive MS (SPMS) — Initially RRMS that gradually transitions to progressive disability accumulation.
Primary Progressive MS (PPMS) — Gradual, continuous worsening from onset without distinct relapses.

Chapter 2

How Stem Cell Therapy Helps

Immune Modulation and Neuroprotection

MSCs exert powerful immunomodulatory effects that calm the autoimmune attack on myelin. They suppress autoreactive T -cells and B-cells responsible for demyelination, promote regulatory T -cell development, release oligodendrocyte-supporting factors that promote remyelination, and provide neuroprotective effects against ongoing neurodegeneration. demonstrated reduced relapse rates and MRI lesion activity in relapsing-remitting MS patients treated with MSCs.

The MESEMS clinical trial program — the largest randomized trial of MSC therapy for MS —

Clinical Outcomes

63%: Reduced Relapse Rate
57%: Reduced MRI Lesion Activity
71%: Stabilized or Improved EDSS

Figures reported in our own patient guide from published studies and our clinical experience. They describe groups of patients, not a prediction for any individual case. See the evidence we rely on.

Chapter 3

Treatment at StemCell Longevita

Our MS Protocol

We use a combination of IV and intrathecal MSC delivery for maximum neurological benefit. The intrathecal route allows direct delivery of cells to the central nervous system, bypassing the blood-brain barrier. Treatment is customized based on MS type, disease activity, and current disease-modifying therapy.

Treatment at Liv Hospital Ulus

Day 1 — Comprehensive neurological examination, MRI review, EDSS assessment, and blood work.
Day 2 — Intrathecal stem cell administration and IV infusion under monitoring.
Day 3 — Follow-up neurological assessment, second IV infusion, and discharge planning.

Chapter 4

Results & Recovery

Expected Timeline

Improvements in fatigue and energy are often among the first benefits, appearing within 4 to 8 weeks. Motor, sensory, and cognitive improvements develop over 3 to 6 months. MRI improvements (reduced lesion activity) may be documented at 6 to 12 month follow-up.

4-8: Weeks to Initial Benefits
74%: Patients Report Improvement
18-24: Months Average Benefit Duration

Figures reported in our own patient guide from published studies and our clinical experience. They describe groups of patients, not a prediction for any individual case. See the evidence we rely on.

Chapter 5

Getting Started

Next Steps

If you have MS and want to explore stem cell therapy, send your MRI reports, neurological assessments, and current treatment regimen for a free evaluation. Our neurology team will provide an honest assessment of expected benefits for your specific case.

Frequently asked questions

While a cure for MS is not yet available, stem cell therapy can significantly reduce disease activity, slow or halt progression, and improve neurological function. Some patients achieve sustained remission of relapse activity.

Not necessarily. The decision depends on which DMT you are on. Some DMTs can be continued alongside stem cell therapy, while others may need temporary adjustment. Our team coordinates with your neurologist on medication management.

While results are most robust in relapsing-remitting MS, patients with progressive MS can also benefit, particularly from the neuroprotective and anti-inflammatory effects. Expectations should be appropriately managed for progressive forms.

Most patients start with one treatment course and may benefit from booster treatments every 12 to 18 months. The frequency depends on disease activity and response to initial treatment.

Next steps

Download the full guide for the complete chapters, clinical detail and the questions to ask any clinic. Our team reviews every enquiry personally and will tell you honestly whether this therapy is appropriate for your case.