Free patient guide · 19 pages · PDF

Stem Cell Therapy for Infertility: A Patient's Guide

Regenerative Solutions for Reproductive Health

Last updated: 2026-09-01 · Medically reviewed by SCL Medical Team

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What is inside this guide

Understanding Infertility
How Stem Cell Therapy Helps
Treatment at StemCell Longevita
Results & Recovery
Getting Started

Chapter 1

Understanding Infertility

What Is Infertility?

Infertility is defined as the inability to conceive after 12 months of regular unprotected intercourse (or 6 months for women over 35). It affects approximately 15% of couples worldwide. Female infertility factors include diminished ovarian reserve, premature ovarian insufficiency, endometriosis, and uterine conditions. Male factors include low sperm count, poor motility, and structural abnormalities.

Common Causes

Age-related decline in ovarian function is the most common cause of female infertility. Stem cell therapy offers hope by potentially rejuvenating ovarian tissue and improving egg quality.

Diminished Ovarian Reserve (DOR) — Reduced number and quality of eggs, often age-related.
Premature Ovarian Insufficiency (POI) — Ovarian failure before age 40, causing early menopause-like symptoms.
Endometriosis — Tissue similar to uterine lining grows outside the uterus, damaging reproductive organs.
Thin endometrium — Inadequate uterine lining thickness preventing embryo implantation.
Male factor — Low sperm count, poor morphology, or reduced motility.

Chapter 2

How Stem Cell Therapy Helps

Reproductive Regeneration

MSC therapy for infertility works by promoting angiogenesis in ovarian tissue to improve blood supply and follicular health, secreting growth factors that stimulate dormant follicles, reducing the inflammatory environment associated with endometriosis, improving endometrial receptivity for embryo implantation, and potentially improving egg quality through paracrine effects on ovarian follicles. Clinical studies have shown that intra-ovarian MSC injection improved AMH levels (a key marker of ovarian reserve) and resulted in natural or IVF-assisted pregnancies in women previously diagnosed with diminished ovarian reserve.

Research Outcomes

43%: Improved AMH Levels
35%: Resumed Menstrual Cycles
28%: Achieved Pregnancy

Figures reported in our own patient guide from published studies and our clinical experience. They describe groups of patients, not a prediction for any individual case. See the evidence we rely on.

Chapter 3

Treatment at StemCell Longevita

Our Fertility Protocol

Treatment includes transvaginal ultrasound-guided intra-ovarian injection of MSCs to directly target ovarian tissue, combined with IV infusion for systemic reproductive health support. For thin endometrium, intrauterine MSC delivery is also available. Treatment is coordinated with your fertility specialist and IVF clinic for optimal timing.

Treatment Process

Day 1 — Comprehensive fertility evaluation including hormonal panel (AMH, FSH, E2), transvaginal ultrasound, and medical history review.
Day 2 — Intra-ovarian MSC injection under transvaginal ultrasound guidance and IV infusion.
Day 3 — Follow-up assessment and coordination with your fertility team for next steps.

Chapter 4

Results & Recovery

Expected Timeline

Hormonal improvements (AMH, FSH) may be detectable within 4 to 8 weeks. Ovarian response to stimulation may improve within 2 to 3 menstrual cycles. The optimal window for IVF following stem cell therapy is typically 3 to 6 months after treatment, when the regenerative effects are most active.

2-3: Cycles to Improved Response
3-6: Months Optimal IVF Window
67%: Improved Ovarian Response

Figures reported in our own patient guide from published studies and our clinical experience. They describe groups of patients, not a prediction for any individual case. See the evidence we rely on.

Chapter 5

Getting Started

Next Steps

If you are struggling with infertility and have not achieved success with conventional treatments, contact us with your fertility assessments and hormone levels for a free evaluation. Our reproductive specialist will discuss how stem cell therapy can support your journey to parenthood.

Frequently asked questions

Some patients have achieved natural pregnancies after stem cell therapy for diminished ovarian reserve. However, most patients combine stem cell therapy with IVF for the best chance of success.

Yes, MSC therapy has been safely combined with IVF protocols. Treatment timing is coordinated with your IVF cycle for optimal results.

Success rates vary based on age, underlying cause, and severity of infertility. In clinical studies, approximately 28-35% of treated patients achieved pregnancy. Results are best for patients under 40 with diminished ovarian reserve.

Yes, early research suggests that MSC therapy may improve sperm parameters in some cases of male infertility. Our team evaluates both partners when assessing treatment options.

Next steps

Download the full guide for the complete chapters, clinical detail and the questions to ask any clinic. Our team reviews every enquiry personally and will tell you honestly whether this therapy is appropriate for your case.