How do stem cells treat liver disease?

MSCs home to damaged liver tissue where they reduce inflammation, reverse fibrosis, stimulate hepatocyte regeneration, and modulate the immune response. This helps restore liver architecture and function.

Can stem cell therapy treat liver cirrhosis?

MSC therapy has shown significant promise for liver cirrhosis. Clinical studies report improvements in MELD scores, albumin levels, and liver function tests. While not reversing all damage, MSCs can significantly improve liver function.

What liver conditions respond to stem cell therapy?

We treat alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), liver cirrhosis, liver fibrosis, and hepatitis-related liver damage. Each condition receives a tailored treatment protocol.

How long does it take to see liver improvements?

Improvements in liver function tests (ALT, AST, albumin, bilirubin) are typically observed within 1-3 months. Fibrosis reduction and structural improvements may take 3-6 months to become apparent on imaging.

Stem Cell Therapy for Hepatitis & Liver Disease

How stem cell therapy may help patients with viral hepatitis, liver fibrosis, and chronic liver disease. MSC treatment for liver regeneration and inflammation reduction.

How MSCs Support Liver Regeneration in Hepatitis

Viral hepatitis (B and C) causes progressive hepatic inflammation, fibrosis, and cirrhosis when immune-mediated hepatocyte damage outpaces the liver's regenerative capacity. MSC therapy addresses both the inflammatory driver and the fibrotic end-organ damage: MSCs suppress hepatic stellate cell (HSC) activation — the primary driver of liver fibrosis — through HGF and IL-10 secretion; reduce TNF-α-mediated hepatocyte apoptosis; promote hepatocyte proliferation; and when engrafted in hepatic tissue, can directly restore hepatic function in damaged zones.

Evidence in Liver Fibrosis and Hepatitis B/C

Published trials from multiple centres (Kharaziha et al. 2009, Mohamadnejad et al. 2007, El-Ansary et al. 2012) in decompensated liver cirrhosis (predominantly hepatitis B/C aetiologies) report improvements in Child-Pugh score, MELD score, serum albumin, and bilirubin at 6–12 months following MSC infusion. A proportion of patients are downgraded from Child-Pugh C to B. Hepatic fibrosis quantification (FibroScan, fibronectin) shows significant reduction in some series. Hepatitis B patients with ongoing viral replication require antiviral therapy concurrently.

Liver Disease Treatment Protocol at StemCell Longevita

Our liver programme delivers 2–3 sessions of IV or hepatic artery-infused WJ-MSCs over 5–7 days, tailored to the degree of hepatic impairment. Pre-treatment liver function panel, FibroScan, abdominal ultrasound, and viral load quantification are mandatory. Patients with Child-Pugh A or B disease are the strongest candidates; Child-Pugh C patients are assessed individually. Hepatology co-management is coordinated throughout the follow-up period.

Frequently Asked Questions

How do stem cells treat liver disease?: MSCs home to damaged liver tissue where they reduce inflammation, reverse fibrosis, stimulate hepatocyte regeneration, and modulate the immune response. This helps restore liver architecture and function.
Can stem cell therapy treat liver cirrhosis?: MSC therapy has shown significant promise for liver cirrhosis. Clinical studies report improvements in MELD scores, albumin levels, and liver function tests. While not reversing all damage, MSCs can significantly improve liver function.
What liver conditions respond to stem cell therapy?: We treat alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), liver cirrhosis, liver fibrosis, and hepatitis-related liver damage. Each condition receives a tailored treatment protocol.
How long does it take to see liver improvements?: Improvements in liver function tests (ALT, AST, albumin, bilirubin) are typically observed within 1-3 months. Fibrosis reduction and structural improvements may take 3-6 months to become apparent on imaging.

Stem Cell Therapy for Hepatitis & Liver Disease

How MSCs Support Liver Regeneration in Hepatitis

Evidence in Liver Fibrosis and Hepatitis B/C

Liver Disease Treatment Protocol at StemCell Longevita

Frequently Asked Questions

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