Crohns Disease Stem Cell Therapy
Autoimmune & Gastroenterology

Stem Cell Therapy for Crohn's Disease

EU-validated MSC approach for intestinal healing, fistula repair, and immune modulation. Addressing the root autoimmune dysfunction driving inflammatory bowel disease.

Révisé médicalement par Équipe Médicale SCL
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Hôtel 5 étoiles
Transferts aéroport
Équipe médicale dédiée
Suivi sur 12 mois
Laboratoire certifié GMP
CSE de la gelée de Wharton
Hôpital accrédité JCI
Voir la recherche et l'éthique
Understanding the Condition

What is Crohn's Disease?

Crohn's disease is a chronic inflammatory bowel disease (IBD) that can affect any part of the gastrointestinal tract, from mouth to anus. It causes inflammation that can lead to abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition. Approximately 3 million adults in the US alone are diagnosed with IBD.

Conventional treatments include immunosuppressants and biologics that manage inflammation but don't heal damaged intestinal tissue. MSC therapy for Crohn's disease has been validated by EU regulatory approval (Alofisel/darvadstrocel) for perianal fistulas, confirming the clinical potential of stem cell approaches.

At StemCell Longevita, we offer comprehensive MSC treatment protocols for Crohn's disease that address both intestinal inflammation and complications like fistulas, using high-quality Wharton's jelly stem cells with proven immunomodulatory properties.

Ideal Candidates

  • Patients with moderate to severe Crohn's disease
  • Those with perianal or intestinal fistulas
  • Patients experiencing frequent disease flares despite medication
  • Individuals seeking to reduce immunosuppressive medication dosage
  • Patients with steroid-dependent or refractory Crohn's disease
Key Benefits

How Stem Cell Therapy Helps Crohn's Disease

Intestinal Healing

MSCs promote mucosal healing and tissue regeneration in the inflamed intestinal lining, reducing ulceration and restoring gut barrier function.

Fistula Repair

Stem cell therapy has EU-validated efficacy for perianal fistulas. MSCs promote tissue repair and closure of fistula tracts, a major complication of Crohn's disease.

Immune Modulation

MSCs rebalance the dysregulated gut immune system, suppressing pathogenic Th1/Th17 responses while promoting regulatory T-cells and anti-inflammatory cytokines.

Reduced Flare Frequency

By addressing underlying immune dysfunction, many patients experience longer periods of remission and reduced frequency and severity of disease flares.

Your Journey

Treatment Process

Your step-by-step treatment journey at StemCell Longevita

01

GI Assessment

Review of endoscopy results, disease activity scoring, fistula evaluation, and comprehensive immune biomarker analysis.

02

Treatment Planning

Personalized protocol based on disease location, complications, current medications, and treatment goals.

03

MSC Preparation

High-quality Wharton's jelly MSCs with validated immunomodulatory properties prepared in our GMP-certified laboratory.

04

Administration

IV infusion for systemic immune modulation, with optional local injection for perianal fistulas or localized disease.

05

Response Tracking

Post-treatment monitoring including symptom scoring, blood markers, and imaging at 3, 6, and 12 months.

Expériences des patients

Résultats réels de patients ayant choisi la médecine régénérative chez StemCell Longevita Istanbul

"Mon rhumatologue a été surpris par l'amélioration. Je peux tenir la main de mes petits-enfants sans grimacer — cela signifie tout pour moi."

Avant:Gonflement sévère des articulations des mains et des poignets, incapacité à ouvrir des bocaux ou à écrire, sous immunosuppresseurs
Après:Gonflement articulaire réduit de 70%, retrouve l'écriture et la cuisine, dose de médicament divisée par deux
Sarah L.
Royaume-Uni·Polyarthrite rhumatoïde

"Le lupus contrôlait ma vie depuis une décennie. Après le traitement à Istanbul, j'ai voyagé dans trois pays en un mois — inimaginable il y a un an."

Avant:Fatigue écrasante, éruptions cutanées, atteinte rénale nécessitant des stéroïdes à fortes doses
Après:Niveau d'énergie nettement amélioré, peau nette, dose de stéroïdes réduite de 60%
Anna B.
Suède·Lupus systémique (LES)
Common Questions

Frequently Asked Questions

Yes, MSC therapy for Crohn's disease has significant clinical validation. Alofisel (darvadstrocel), an MSC-based therapy, received EU regulatory approval for treating complex perianal fistulas in Crohn's patients. Our approach extends this validated principle to broader intestinal inflammation management.

Absolutely. Fistula healing is one of the strongest evidence-based applications of MSC therapy in Crohn's disease. MSCs promote tissue repair, reduce local inflammation, and support fistula tract closure. Clinical trials show 50-70% complete fistula closure rates with MSC treatment.

Many patients are able to reduce their immunosuppressive medication dosage under their gastroenterologist's supervision after successful MSC therapy. The goal is to achieve better disease control with less pharmacological immunosuppression, though medication changes should always be guided by your treating physician.
Free PDF Guide

Download Our Free Crohn's Disease Guide

Get our comprehensive patient guide with detailed treatment information, expected outcomes, and FAQs — all in one downloadable PDF.

Take the First Step

Ready to Explore Crohn's Disease Treatment?

Schedule a free consultation with our medical team to discuss your condition and learn how stem cell therapy may help.